Visser will replace Jesse Kriel who has been named on the bench for this match, the first of two on Australian soil for the Vodacom Bulls in the Vodacom Super Rugby competition.
Visser joined the squad on Monday in place of injured Jan Serfontein and with Kriel recovering from a knee contusion, Ludeke opted for the 30 times capped fullback to start.
This will be a first start at fullback for Visser since the opening week in February against the DHL Stormers.
Serfontein has been replaced by Burger Odendaal in the midfield.
In the pack, there is a return for Adriaan Strauss, who was rested last weekend, with Callie Visagie moving to the bench, as well as a first start on tour for Grant Hattingh, who replaces Victor Matfield at lock. Matfield is rested according to the SARU agreement.
Dean Greyling rotates with Trevor Nyakane at loose head and Arno Botha swops places with Jacques du Plessis at the side of the scrum in the other change to the pack.
The team (with number of Super rugby caps) is: Jurgen Visser (30), Francois Hougaard (85), JJ Engelbrecht (62), Burger Odendaal (7), Bjorn Basson (84), Handré Pollard (24), Rudy Paige (18), Pierre Spies (116, c), Arno Botha (30), Deon Stegmann (91), Grant Hattingh (45), Flip van der Merwe (78), Marcel van der Merwe (30), Adriaan Strauss (116), Dean Greyling (65). Replacements: Callie Visagie (48), Trevor Nyakane (55), Werner Kruger (111), Jacques du Plessis (28), Lappies Labuschagne (37), Jacques Louis Potgieter (59), Travis Ismaiel (3), Jesse Kriel (14). - ANA
Original source: Bulls pick Visser at fullback